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New, Highly Efficient Work‐Up Protocol for Sulfonated Diphosphines
Author(s) -
Mul Wilhelmus P.,
Ramkisoensing Kevita,
Kamer Paul C. J.,
Reek Joost N. H.,
van der Linden Arjan J.,
Marson Angelica,
van Leeuwen Piet W. N. M.
Publication year - 2002
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/1615-4169(200206)344:3/4<293::aid-adsc293>3.0.co;2-o
Subject(s) - chemistry , diphosphines , sulfuric acid , neutralization , sulfate , filtration (mathematics) , ligand (biochemistry) , combinatorial chemistry , organic chemistry , catalysis , virology , biochemistry , virus , statistics , mathematics , receptor , biology
Isolation of a series of sulfonated diphosphines via a new highly efficient method is described. The work‐up procedure involves the precipitation of the sulfonated ligand prior to neutralization, and subsequent removal of the sulfuric acid by filtration and washing. Great advantages of this procedure are its simplicity and easiness to scale‐up while co‐production of large amounts of sulfate salts is avoided.