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Fluoroalkyldistannoxane Catalysts for Transesterification in Fluorous Biphase Technology
Author(s) -
Xiang Jiannan,
Orita Akihiro,
Otera Junzo
Publication year - 2002
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/1615-4169(200201)344:1<84::aid-adsc84>3.0.co;2-c
Subject(s) - transesterification , chemistry , catalysis , toluene , organic chemistry , alcohol , solvent
Novel, practical protocols of transesterification have been advanced with recourse to fluorous biphase technology. The fluoroalkyldistannoxane catalysts enable transesterification in FC‐72 solvent to furnish 100% yields of the desired esters by use of reactants ester and alcohol in a 1 : 1 ratio. The catalysts also work in FC‐72/organic solvent system as well as in toluene alone. A number of esters and alcohols bearing various functional groups are employable. The catalysts can be totally recovered and reused. More conveniently, the catalyst solution in FC‐72 which is separated from the reaction mixture is directly used for the next reaction.