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Palladium‐Catalyzed Intramolecular Coupling of Aryl Halides and Ketone Enolates: Synthesis of Hexahydro‐2,6‐methano‐1‐2
Author(s) -
Solé Daniel,
Vallverdú Lluís,
Bonjoch Josep
Publication year - 2001
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/1615-4169(200107)343:5<439::aid-adsc439>3.0.co;2-g
Subject(s) - chemistry , palladium , aryl , intramolecular force , halide , ketone , catalysis , methyl ketone , coupling (piping) , medicinal chemistry , organic chemistry , alkyl , mechanical engineering , engineering
The palladium‐catalyzed intramolecular coupling of 2‐haloanilines and ketone enolates is a useful methodology for the synthesis of hexahydro‐2,6‐methano‐1‐2 derivatives. A study about the reaction conditions of the process is reported.