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Palladium‐Catalyzed Three‐Component Synthesis of Functionalized Allylamines by Intermolecular Tandem Carbopalladation–Amination
Author(s) -
Laren Martijn W. van,
Diederen Jeroen J. H.,
Elsevier Cornelis J.
Publication year - 2001
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/1615-4169(20010330)343:3<255::aid-adsc255>3.0.co;2-t
Subject(s) - chemistry , iodobenzene , palladium , allene , catalysis , amination , hydroamination , stereoselectivity , tandem , regioselectivity , amine gas treating , organic chemistry , combinatorial chemistry , medicinal chemistry , materials science , composite material
Highly regio‐ and stereoselective formation of allylamines has been achieved through a three‐component reaction between iodobenzene, an allene, and an amine in acetonitrile, catalyzed by in situ formed and by isolated palladium‐diphosphine catalysts.