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Effects of psycho–physical stress (competitive rafting) on saliva interleukin‐1 beta
Author(s) -
Ilardo Claudio,
Toniolo AnneMarie,
AimoneGastin Isabelle,
Abdelmouttaleb Idrissia,
Guéant JeanLouis,
Desor Didier
Publication year - 2001
Publication title -
stress and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 61
eISSN - 1532-2998
pISSN - 1532-3005
DOI - 10.1002/1532-2998(200101)17:1<9::aid-smi871>3.0.co;2-y
Subject(s) - saliva , basal (medicine) , medicine , circadian rhythm , endocrinology , immune system , secretion , interleukin , interleukin 6 , psychology , cytokine , immunology , insulin
The effects of psycho‐physical stress on immune function were evaluated by investigating the secretion rate of salivary interleukin‐1 beta (IL‐1β) during competitive rafting. Ten female and 20 male volunteers participated in this study. The concentration of IL‐1 β was determined in saliva using ELISA. We examined the statistical differences between T2/T1 (the changes observed during the training period) and C2/C1 (the changes before and after the competitive rafting) ratios by a Wilcoxon signed rank test. The ratio of IL‐1 β was significantly increased during competitive rafting ( C 2& sol ; C 1 = 3.6; p < 0.01), compared to the control ratio ( T 2& sol ; T 1 = 0.95; p < 0.01). The level of IL‐1 β at 8.00 a.m. decreased significantly between the first (11.9 ± 8.71 pmol/l) and the third day (7.9 ± 5.52 pmol/l) in all subjects (p < 0.01). In addition, the basal IL‐1 β levels significantly decreased between the beginning (8.00 a.m.) and the end of the day (6.00 p.m.), during the three consecutive days of collection (p < 0.01). These results may correspond to a circadian secretion rhythm of human saliva IL‐1 β. In conclusion, a disturbance of IL‐1 β salivary secretion is observed either after psycho‐physical stress or during intensive training. It may potentially affect the immune and endocrine status. Copyright © 2001 John Wiley & Sons, Ltd.