Open AccessAscites as the major manifestation of systemic lupus erythematosus
Author(s) -
Bitran Jacob,
McShane Dennis,
Ellman Michael H.
Publication year - 1976
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/1529-0131(197607/08)19:4<782::aid-art1780190421>3.0.co;2-i
Subject(s) - ascites , medicine , peritoneum , prednisone , pathology , inflammation , peritoneal cavity , cyclophosphamide , laparotomy , lupus erythematosus , immunology , gastroenterology , chemotherapy , antibody , surgery
It is uncommon for ascites secondary to severe peritoneal inflammation to be the major manifestation of systemic lupus erythematosus. Chronic nonspecific inflammation with a granular type immunofluorescent staining along the mesothelial layer of the peritoneum and peritoneal blood vessels was demonstrated in peritoneal tissue obtained at laparotomy. Paramyxovirus‐like structures were seen within vascular endothelium. The ascites diminished with high‐dose prednisone and cyclophosphamide therapy.