Open AccessCombination therapy with naproxen and aspirin in rheumatoid arthritis
Author(s) -
Willkens Robert F.,
Segre Eugene J.
Publication year - 1976
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/1529-0131(197607/08)19:4<677::aid-art1780190404>3.0.co;2-a
Subject(s) - naproxen , medicine , aspirin , rheumatoid arthritis , placebo , crossover study , arthritis , alternative medicine , pathology
Thirty‐six patients with rheumatoid arthritis were studied to determine the effectiveness and safety of combined therapy with naproxen and aspirin. An 8‐week double‐blind crossover trial was performed in which naproxen and placebo were administered on a background of constant‐dose aspirin. Combination therapy was demonstrated to be more effective than aspirin alone. Tolerance of the two regimens was comparable.