Open AccessAllergy in systemic lupus erythematosus. IgE levels and reaginic phenomenon
Author(s) -
Goldman John A.,
Klimek Grace Ann,
Ali Rida
Publication year - 1976
Publication title -
arthritis & rheumatism
Language(s) - English
Resource type - Journals
eISSN - 1529-0131
pISSN - 0004-3591
DOI - 10.1002/1529-0131(197607/08)19:4<669::aid-art1780190403>3.0.co;2-e
Subject(s) - medicine , immunoglobulin e , rheumatoid arthritis , immunology , allergy , lupus erythematosus , arthritis , drug allergy , antibody
Twenty‐seven patients with systemic lupus erythematosus (SLE) were investigated for the presence of allergic reactivity, and serum IgE levels were measured by immunoassay. Compared to controls, SLE patients had significant increases of only allergic rhinitis and drug allergy. Despite the usual hyperimmunoglobulinemia in SLE, IgE levels were not elevated (mean: 251 IU). Because recent reports have noted elevated IgE in rheumatoid arthritis, this finding may suggest basic immunologic differences between rheumatoid arthritis and SLE.