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Pesticidal properties of parthenin (from Parthenium hysterophorus ) and related compounds
Author(s) -
Datta Subhendu,
Saxena Dinesh B
Publication year - 2001
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/1526-4998(200101)57:1<95::aid-ps248>3.0.co;2-j
Subject(s) - parthenium hysterophorus , cassia tora , sesquiterpene lactone , spodoptera litura , mythimna separata , pyrazoline , lactone , radicle , biology , allelopathy , chemistry , sesquiterpene , organic chemistry , stereochemistry , botany , germination , weed , larva , medicine , alternative medicine , pathology
Eleven sesquiterpene lactone derivatives of parthenin ( 1 ), obtained from wild feverfew, Parthenium hysterophorus , were prepared by chemical and photochemical transformations. The compounds tested were a pyrazoline adduct ( 2 ) of parthenin, its cyclopropyl ( 3 ) and propenyl ( 4 ) derivatives, anhydroparthenin ( 5 ), a dihydro‐deoxygenated product ( 6 ), a formate ( 7 ) and its corresponding alcohol ( 8 ) and acetate ( 9 ), a rearranged product ( 10 ), lactone ( 11 ) and hemiacetal ( 12 ). All these derivatives, along with parthenin, were tried for their antifeedant action against sixth‐instar larvae of Spodoptera litura , for insecticidal activity against the adults of store grain pest Callosobruchus maculatus , for phytotoxic activity against Cassia tora , and for nematicidal activity against the juvenile stage‐II (J 2 ) of the root knot nematode Meloidogyne incognita . Antifeedent bioassay revealed that parthenin is moderately antifeedant. Among the derivatives, the saturated lactone ( 11 ) was found to be about 2.25 times more active than parthenin. The pyrazoline adduct ( 2 ) was found to be the most effective as an insecticide, with LC 50 values after 24, 48 and 72 h of 96, 43 and 32 mg litre −1 , respectively, which are comparable with neem extract. Compound 4 was found to be the most effective inhibitor of germination and seedling growth of C tora , with ID 50 values for germination, plumule length and radicle length of 136, 326 and 172 compared with 364, 738 and 427 mg litre −1 , respectively, for parthenin. Compound 10 was found to be the most effective in terms of nematicidal activity. The LC 50 values for this compound were 273 and 104 mg litre −1 , respectively, after 48 and 72 h compared with 862 and 512 mg litre −1 observed for parthenin after 48 and 72 h. © 2001 Society of Chemical Industry