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Recent developments in amperometric detection for microchip capillary electrophoresis
Author(s) -
Vandaveer Walter R.,
Pasas Stephanie A.,
Martin R. Scott,
Lunte Susan M.
Publication year - 2002
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/1522-2683(200211)23:21<3667::aid-elps3667>3.0.co;2-w
Subject(s) - amperometry , capillary electrophoresis , microfluidics , chromatography , nanotechnology , electrophoresis , materials science , chemistry , electrode , electrochemistry
The interest in microfluidic devices has increased considerably over the past decade due to the numerous advantages of working within a miniature, microfabricated format. This review focuses on recent advances in coupling amperometric detection with microchip capillary electrophoresis (CE). Advances in electrochemical cell design, isolation of the detector from the separation field, and integration of both pre‐ and postseparation reaction chambers are discussed. The use of microchip CE with amperometric detection for enzyme/immunoassays, clinical and environmental assays, and the determination of neurotransmitters is described.