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Components for integrated poly(dimethylsiloxane) microfluidic systems
Author(s) -
Ng Jessamine M. K.,
Gitlin Irina,
Stroock Abraham D.,
Whitesides George M.
Publication year - 2002
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/1522-2683(200210)23:20<3461::aid-elps3461>3.0.co;2-8
Subject(s) - microfluidics , interfacing , fabrication , materials science , soft lithography , nanotechnology , polymer , pdms stamp , computer science , composite material , computer hardware , medicine , alternative medicine , pathology
This review describes the design and fabrication of microfluidic systems in poly(dimethylsiloxane) (PDMS). PDMS is a soft polymer with attractive physical and chemical properties: elasticity, optical transparency, flexible surface chemistry, low permeability to water, and low electrical conductivity. Soft lithography makes fabrication of microfluidic systems in PDMS particularly easy. Integration of components, and interfacing of devices with the user, is also convenient and simpler in PDMS than in systems made in hard materials. Fabrication of both single and multilayer microfluidic systems is straightforward in PDMS. Several components are described in detail: a passive chaotic mixer, pneumatically actuated switches and valves, a magnetic filter, functional membranes, and optical components.