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Characterization of dendrimer properties by capillary electrophoresis and their use as pseudostationary phases
Author(s) -
Castagnola Massimo,
Zuppi Cecilia,
Rossetti Diana V.,
Vincenzoni Federica,
Lupi Alessandro,
Vitali Alberto,
Meucci Elisabetta,
Messana Irene
Publication year - 2002
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/1522-2683(200206)23:12<1769::aid-elps1769>3.0.co;2-i
Subject(s) - dendrimer , micellar electrokinetic chromatography , electrokinetic phenomena , capillary electrophoresis , chemistry , electrophoresis , hydrodynamic radius , amine gas treating , capillary action , chromatography , analytical chemistry (journal) , electrolyte , micelle , materials science , polymer chemistry , organic chemistry , aqueous solution , composite material , electrode
The general properties of dendrimers and in particular their electrolytic characteristics that are relevant in electrokinetic separations, are described. In order to confirm theoretical considerations on commercial dendrimer charge and hydrodynamic radius, several capillary zone electrophoresis (CZE) experiments were performed. Electrophoretic mobilities measured at different pH values indicated a sensible increase of dendrimer hydrodynamic radius at pH values lower than 2.5. This was probably due to the Coulombic repulsion of charged amine groups of the inner dendrimer shells. The principal reasons that should address the use of dendrimers as pseudostationary phases in micellar electrokinetic chromatography (MEKC) are discussed. Moreover, a survey of different separations performed utilizing dendrimers in MEKC as well as of several future plausible uses of various classes of dendrimers is presented.