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Special aspects of detection methodology in nonaqueous capillary electrophoresis
Author(s) -
Matysik FrankMichael
Publication year - 2002
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/1522-2683(200202)23:3<400::aid-elps400>3.0.co;2-3
Subject(s) - capillary electrophoresis , detector , chromatography , chemistry , mass spectrometry , organic solvent , capillary action , aqueous solution , analytical chemistry (journal) , materials science , computer science , engineering , chemical engineering , organic chemistry , telecommunications , composite material
Over the recent years considerable efforts have been directed to the design of powerful detector arrangements for capillary electrophoresis (CE). The analytical characteristics of the detector have a great influence on the overall analytical performance of CE investigations. The major detection methods in CE, such as UV‐Vis absorbance, fluorescence, mass spectrometry and electrochemical detection, have successfully been adapted also to nonaqueous capillary electrophoresis (NACE). However, the different properties of organic solvent systems require some modification of detector concepts and design compared to aqueous CE. The advances of detector development and application in NACE are reported and discussed with emphasis on methodical aspects.