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A method for UV‐bonding in the fabrication of glass electrophoretic microchips
Author(s) -
Huang Zhili,
Sanders Joshua C.,
Dunsmor Celeste,
Ahmadzadeh Hossein,
Landers James P.
Publication year - 2001
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/1522-2683(200110)22:18<3924::aid-elps3924>3.0.co;2-4
Subject(s) - fabrication , microchannel , electrophoresis , materials science , capillary electrophoresis , nanotechnology , anodic bonding , capillary action , optoelectronics , chromatography , layer (electronics) , chemistry , composite material , medicine , alternative medicine , pathology
This paper presents an approach for the development of methodologies amenable to simple and inexpensive microchip fabrication, potentially applicable to dissimilar materials bonding and chip integration. The method involves a UV‐curable glue that can be used for glass microchip fabrication bonding at room temperature. This involves nothing more than fabrication of glue “guide channels” into the microchip architecture that upon exposure to the appropriate UV light source, bonds the etched plate and cover plate together. The microchip performance was verified by capillary zone electrophoresis (CZE) of small fluorescent molecules with no microchannel surface modification carried out, as well as with a DNA fragment separation following surface modification. The performance of these UV‐bonded electrophoretic microchips indicates that this method may provide an alternative to high temperature bonding.