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Neoengleromycin, a Novel Compound from Engleromyces goetzii
Author(s) -
Jikai Liu,
Jianwen Tan,
Zejun Dong,
Zhihui Ding,
Xianghua Wang,
Peigui Liu
Publication year - 2002
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/1522-2675(200205)85:5<1439::aid-hlca1439>3.0.co;2-x
Subject(s) - chemistry , stereochemistry , hydroxamic acid , cytochalasin , cytochalasin d , chemical structure , organic chemistry , biochemistry , cytoskeleton , cell
A novel N‐containing compound, neoengleromycin ( 1 ) was isolated from the fruiting bodies of the ascomycete Engleromyces goetzii together with two known cytochalasins: cytochalasin D ( 2 ) and 19,20‐epoxycytochalasin D ( 3 ). Structures were established by spectroscopic (including 2D‐NMR) and chemical means. Neoengleromycin ( 1 ) possesses the rare structure of an N ‐substituted hydroxamic acid and represents a new type of natural products.