Premium
Two Novel Lycopodium Alkaloids from Huperzia serrata
Author(s) -
Tan ChangHeng,
Ma XiaoQiang,
Chen GuoFu,
Zhu DaYuan
Publication year - 2002
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/1522-2675(200204)85:4<1058::aid-hlca1058>3.0.co;2-q
Subject(s) - lycopodium , chemistry , herb , huperzine a , boswellia serrata , stereochemistry , botany , traditional medicine , medicinal herbs , organic chemistry , biology , medicine , enzyme , alternative medicine , pathology , acetylcholinesterase
Huperzine Q ( 1 ) and N ‐oxyhuperzine Q ( 2 ), two novel irregular fawcettimine‐type Lycopodium alkaloids were isolated from the CHCl 3 fraction of the basic material of the whole plant of the Chinese medicinal herb Huperzia serrata. Their structures were determined as 13‐epi‐13 β ,16‐epoxydihydrofawcettimine ( 1 ) and N ‐oxy‐13‐epi‐13 β ,16‐epoxydihydrofawcettimine ( 2 ) by means of spectroscopic studies and X‐ray crystallographic analysis.