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2‐Chloro‐3‐(dimethylamino)prop‐2‐enoyl Fluoride, a Stable Acyl Fluoride
Author(s) -
Steiner Eginhard,
Winkler Tammo,
Lang Rober W.
Publication year - 2002
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/1522-2675(200202)85:2<516::aid-hlca516>3.0.co;2-1
Subject(s) - chemistry , silylation , formylation , fluoride , medicinal chemistry , chloride , acetyl chloride , double bond , fluorine , organic chemistry , catalysis , inorganic chemistry
The title compound is formed as a side‐product in the reaction of CF 3 CCl 3 with Zn/DMF and dimethyl(thexyl)silyl chloride (=dimethyl(1,1,2‐trimethylpropyl)silyl chloride). The structure and the double‐bond configuration are deduced from its 13 C‐NMR data. Its formation is discussed in terms of a Vilsmeier ‐type formylation and a reductive elimination.