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Aqueous Systems for Liquid Scintillation Counting: Use of Hydrotropes
Author(s) -
Meyer HansJoachim,
Hoffmann Frank,
Wolff Thomas
Publication year - 2001
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/1522-2675(20011219)84:12<3600::aid-hlca3600>3.0.co;2-f
Subject(s) - chemistry , liquid scintillation counting , aqueous solution , scintillator , fluorescence , aqueous medium , chromatography , nuclear chemistry , radiochemistry , organic chemistry , detector , physics , quantum mechanics , electrical engineering , engineering
Liquid hydrotropic systems, i.e. , mixtures of hydrotropes and water‐forming hydrophilic and hydrophobic regions, allow the solubilization of organic scintillators in essentially aqueous media. Such systems were applied to liquid scintillation counting with 4‐[4‐(5‐phenyloxazol‐2‐yl)benzyl]morpholine as scintillator, a 2,5‐diphenyloxazole (PPO) derivative that proved well‐soluble in acidic hydrotrope systems. Its fluorescence properties were studied. Phenylalanine labeled with 3 H or 14 C was used to test counting. While 14 C counting worked acceptably, 3 H counting was comparatively inefficient, probably due to the short lifetime of β ‐particles in aqueous environments.