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Hydrolysis of tRNA Phe on Suspensions of Amino Acids
Author(s) -
Gao Kui,
Orgel Leslie E.
Publication year - 2001
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/1522-2675(20010613)84:6<1347::aid-hlca1347>3.0.co;2-2
Subject(s) - chemistry , hydrolysis , aspartic acid , glutamic acid , asparagine , glutamine , adsorption , homogeneous , amino acid , acid hydrolysis , organic chemistry , chromatography , biochemistry , physics , thermodynamics
RNA is adsorbed strongly on suspensions of many moderately soluble organic solids. In some cases, the hydrolysis of tRNA Phe is greatly accelerated by adsorption, and the major sites of hydrolysis are changed from those that are important in homogeneous solution. Here we show that the hydrolysis is greatly accelerated by suspensions of aspartic acid and β ‐glutamic acid but not by suspensions of α ‐glutamic acid, asparagine, or glutamine.