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Synthesis of ω ‐Substituted Alkanethiols and (Bromomethyl)methylthiomalonates
Author(s) -
Pfammatter Michael J.,
Siljegovic Vuk,
Darbre Tamis,
Keese Reinhart
Publication year - 2001
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/1522-2675(20010321)84:3<678::aid-hlca678>3.0.co;2-y
Subject(s) - chemistry , stereochemistry , combinatorial chemistry , computational chemistry , organic chemistry
Several multifunctional derivatives of methylthiomalonic acid (=2‐(thiocarboxy)acetic acid), i.e. 20a , b , 21 , 22a, b , and 24 , were prepared from thiols bearing a functionalized head group, i.e. from 9a , b , 12 , and 16d , f ( Schemes 4 and 5 ). The association constants of the two dithio podands 8b and 11 with K + were determined.