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A Mild Approach to the Synthesis of sn ‐Glycerol 1,2‐Di‐ γ ‐linolenate 3‐Palmitate
Author(s) -
Rejzek Martin,
Vacek Miroslav,
Wimmer Zdeněk
Publication year - 2000
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/1522-2675(20001004)83:10<2756::aid-hlca2756>3.0.co;2-i
Subject(s) - chemistry , glycerol , yield (engineering) , linolenate , organic chemistry , fatty acid , materials science , metallurgy
A synthetic approach comprising several studied modifications was applied to the preparation of sn ‐glycerol 1,2‐di‐ γ ‐linolenate 3‐palmitate ( 4 ). Thereby, a convenient and mild synthetic method was elaborated, affording 4 from 1,2‐ O ‐isopropylidene‐ sn ‐glycerol ( 1 ) in an average yield of 65 – 75% and analytically acceptable purity.