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Assessment of thermal tissue ablation with MR elastography
Author(s) -
Wu Tao,
Felmlee Joel P.,
Greenleaf James F.,
Riederer Stephen J.,
Ehman Richard L.
Publication year - 2001
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/1522-2594(200101)45:1<80::aid-mrm1012>3.0.co;2-y
Subject(s) - elastography , thermal ablation , ablation , nuclear magnetic resonance , materials science , radiology , nuclear medicine , biomedical engineering , medicine , ultrasound , physics
An important part of thermal ablation therapy is the assessment of the spatial extent of tissue coagulation. In this work, the mechanical properties of thermally‐ablated tissue were quantitatively evaluated using magnetic resonance elastography (MRE). This study shows that the mechanical properties of focused ultrasound ablated tissue are significantly different from normal tissue, and the difference can be imaged and measured using MRE. Repeated experiments revealed a reproducible pattern of tissue mechanical property change during thermal ablation in ex vivo bovine muscle. This pattern may reflect changes in intrinsic tissue structure and could be used to evaluate tissue coagulation during thermal ablation therapy. Magn Reson Med 45:80–87, 2001. © 2001 Wiley‐Liss, Inc.