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Ultrafast MR grid‐tagging sequence for assessment of local mechanical properties of the lungs
Author(s) -
Chen Qun,
Mai Vu M.,
Bankier Alexander A.,
Napadow Vitaly J.,
Gilbert Richard J.,
Edelman Robert R.
Publication year - 2001
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/1522-2594(200101)45:1<24::aid-mrm1004>3.0.co;2-6
Subject(s) - computer science , grid , flip angle , nuclear magnetic resonance , magnetic resonance imaging , physics , radiology , medicine , mathematics , geometry
While MR imaging with tagged magnetization has shown great utility in the study of muscle mechanics, the evaluation of pulmonary mechanics has long been hindered by the technical difficulties in MR imaging of lung parenchyma. In this study, a fast MR grid‐tagging technique is described for dynamic assessment of regional pulmonary deformation. The method is based on a fast FLASH sequence with short TR and short TE. Tagging was achieved by using double DANTE pulse train or inversion pulses. Our results show that this technique is able to detect changes of the tagging grid caused by physiological deformation of the lung. Quantitative analysis of the data shows that this method is capable of assessing local pulmonary mechanics. The application of this technique could improve our understanding of ventilatory control, and thus provide a unique metric for assessing pulmonary disorders. Magn Reson Med 45:24–28, 2001. © 2001 Wiley‐Liss, Inc.