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Monitoring water content in deforming intervertebral disc tissue by finite element analysis of MRI data
Author(s) -
Kingma Idsart,
van Dieën Jaap H.,
Nicolay Klaas,
Maat Johan J.,
Weinans Harrie
Publication year - 2000
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/1522-2594(200010)44:4<650::aid-mrm21>3.0.co;2-0
Subject(s) - intervertebral disc , signal (programming language) , finite element method , deformation (meteorology) , biomedical engineering , materials science , magnetic resonance imaging , intervertebral disk , nuclear magnetic resonance , anatomy , composite material , medicine , physics , radiology , computer science , lumbar , programming language , thermodynamics
Mechanical loading, occurring during normal daily life, causes fluid to be expelled from intervertebral discs. Excessive fluid loss during heavy loading might make the disc more vulnerable to damage. In this study, fluid loss was investigated in vitro through monitoring the loss of MRI signal intensity in four bovine coccygeal intervertebral discs, compressed at 2000 N during 1.5 hr. The MRI signals were analyzed with the aid of finite element models to account for the deformation of the tissue. A gradual signal loss over time was found during loading, the most pronounced loss occurring in the central disc region. Initial patterns of signal distribution were quite variable between specimens but repeatable within specimens. Magn Reson Med 44:650–654, 2000. © 2000 Wiley‐Liss, Inc.