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Detection and localization of pulmonary air leaks using laser‐polarized 3 He MRI
Author(s) -
Roberts David A.,
Rizi Rahim R.,
Lipson David A.,
Aranda Margaret,
Baumgardner James,
Bearn Lisa,
HansenFlaschen John,
Gefter Warren B.,
Hatabu Hiroto H.,
Leigh Jr. John S.,
Schnall Mitchell D.
Publication year - 2000
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/1522-2594(200009)44:3<379::aid-mrm6>3.0.co;2-4
Subject(s) - coronal plane , nuclear medicine , high resolution , leak , materials science , nuclear magnetic resonance , medicine , radiology , physics , geology , remote sensing , thermodynamics
Pulmonary air leaks were created in the lungs of Yorkshire pigs. Dynamic, 3D MRI of laser‐polarized 3 He gas was then performed using a gradient‐echo pulse sequence. Coronal magnitude images of the helium distribution were acquired during gas inhalation with a voxel resolution of approximately 1.2 × 2.5 × 8 mm, and a time resolution of 5 sec. In each animal, the ventilation images reveal focal high‐signal intensity within the pleural cavity at the site of the air leaks. In addition, a wedge‐shaped region of increased parenchymal signal intensity was observed adjacent to the site of the air leak in one animal. 3 He MRI may prove helpful in the management of patients with pulmonary air leaks. Magn Reson Med 44:379–382, 2000. © 2000 Wiley‐Liss, Inc.