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Facilitation of electric forepaw stimulation‐induced somatosensory activation in rats by additional acoustic stimulation: An fMRI investigation
Author(s) -
Burke M.,
Schwindt W.,
Ludwig U.,
Hennig J.,
Hoehn M.
Publication year - 2000
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/1522-2594(200008)44:2<317::aid-mrm20>3.0.co;2-r
Subject(s) - somatosensory system , facilitation , stimulation , functional magnetic resonance imaging , communication noise , neuroscience , noise (video) , scanner , magnetic resonance imaging , blood oxygenation , nuclear magnetic resonance , medicine , psychology , physics , computer science , artificial intelligence , radiology , linguistics , philosophy , image (mathematics)
The influence of scanner acoustic noise on somatosensory activation pattern in rat cortex was investigated by functional magnetic resonance imaging (fMRI) using the blood oxygenation level‐dependent (BOLD) contrast. This was achieved by two approaches. The first approach was to compare a conventional, loud fMRI sequence with a new sequence, in which the noise level was reduced by about 30 dB. In the second approach, the inner ear of the animal was destroyed, resulting in deafness. We compared the activation patterns obtained with both sequences before and after cochleotomy. The activated area was larger when data were sampled with background noise, and was also larger before cochleotomy than after. Thus, facilitation of somatosensory activation is induced by additional acoustic stimulation. Magn Reson Med 44:317–321, 2000. © 2000 Wiley‐Liss, Inc.