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Imaging of water and fat fractions in high‐field MRI with multiple slice chemical shift‐selective inversion recovery
Author(s) -
Laurent W.M.,
Bonny J.M.,
Renou J.P.
Publication year - 2000
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/1522-2586(200009)12:3<488::aid-jmri15>3.0.co;2-5
Subject(s) - specific absorption rate , nuclear magnetic resonance , magnetic resonance imaging , adiabatic process , analytical chemistry (journal) , chemistry , noise immunity , pulse sequence , materials science , physics , chromatography , thermodynamics , computer science , radiology , medicine , telecommunications , antenna (radio) , quantum mechanics , electronic circuit
Fat and water fractions were quantified at high field using a chemical shift‐selective inversion recovery (CSS‐IR) sequence to address the major difficulties encountered at high field by phase‐sensitive techniques used for fat/water discrimination. Water‐ and fat‐suppressed images were perfectly registered, which is a prerequisite for quantification. Immunity of the inversion pulse to B 1 field modulations and off‐resonance effects was tested for two adiabatic inversion pulses, with hyperbolic secant and asymmetric hyper‐pulse waveforms. Taking into account adiabaticity, immunity to off‐resonance, radiofrequency power requirements, and specific absorption rate, the former was chosen. A close correlation was found between fat content measured by CSS‐IR at 4.7 T (R 2 = 0.97, P < 0.001) and 9.4 T (R 2 = 0.99, P < 0.05) and that measured by Soxhlet extraction. Different sources of bias (lowsignal‐to‐noise ratio, magnetization transfer effect) are discussed. J. Magn. Reson. Imaging 2000;12:488–496. © 2000 Wiley‐Liss, Inc.

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