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Endometrial carcinoma: Assessment of myometrial invasion with plain and gadolinium‐enhanced MR imaging
Author(s) -
Saez Fermín,
Urresola Arantza,
Larena Jose A.,
Martín Jose I.,
Pijuán Jose I.,
Schneider Jose,
Ibáñez Eduardo
Publication year - 2000
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/1522-2586(200009)12:3<460::aid-jmri12>3.0.co;2-3
Subject(s) - magnetic resonance imaging , medicine , gadolinium , predictive value , carcinoma , radiology , predictive value of tests , nuclear medicine , pathology , chemistry , organic chemistry
The purpose of this study was to determine the accuracy of magnetic resonance imaging (MRI) for evaluating the depth of myometrial invasion, potential sources of pitfalls, and the usefulness of contrast‐enhanced series. Eighty‐five patients with a pathologic diagnosis of endometrial carcinoma underwent preoperative MRI (plain and contrast‐enhanced). Grade of myometrial invasion, presence of junctional zone (JZ), fibromyomas, and tumoral thickness were evaluated by two groups of radiologists blinded to pathologic results. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI in determining the depth of myometrial invasion were evaluated. The sensitivity/specificity for plain MR was 64.1–64.1/93.5–100 for both observers. Assessing deep myometrial invasion, sensitivity, and NPV improved significantly ( P = 0.002, P = 0.003 for both observers) when comparing plain and whole study series. Tumoral thickness ( P = 0.16, P = 0.13, for the two observers) and presence or absence of JZ ( P = 0.41, P = 0.14) did not influence myometrial invasion assessment. Gadolinium‐enhanced series improve the assessment of deep myometrial invasion in endometrial carcinoma. J. Magn. Reson. Imaging 2000;12:460–466. © 2000 Wiley‐Liss, Inc.