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Changes in left and right ventricular cardiac function after valve replacement for aortic stenosis determined by cine MR imaging
Author(s) -
Sandstede J.J.W.,
Beer M.,
Hofmann S.,
Lipke C.,
Harre K.,
Pabst T.,
Kenn W.,
Neubauer S.,
Hahn D.
Publication year - 2000
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/1522-2586(200008)12:2<240::aid-jmri5>3.0.co;2-6
Subject(s) - medicine , ejection fraction , cardiology , stenosis , body surface area , aortic valve replacement , magnetic resonance imaging , aortic valve stenosis , valve replacement , left ventricular hypertrophy , radiology , heart failure , blood pressure
The purpose of this study was to determine the changes in function of both the left and the right ventricles (LV, RV) before and after aortic valve replacement (AVR), compared with age‐matched healthy volunteers using magnetic resonance (MR) imaging. Fourteen patients with aortic stenosis underwent MR imaging (1.5 T) before and 3 ( n = 14) and 12 ( n = 9) months after surgical valve replacement. An electrocardiographically triggered two‐dimensional cine fast low‐angle shot sequence was used for the evaluation of absolute values and indices related to 1 m2body surface area for function, mass, and LV wall thickening. Fourteen age‐matched healthy volunteers served as controls. Before surgery, all patients showed significant abnormalities of LV mass and function, whereas RV mass and function were not different from those of volunteers and remained mostly unchanged. After surgery, normalization of LV ejection fraction, absolute mass, and end‐systolic wall thickness was observed, whereas the LV mass index failed to normalize, and LV volumes remained elevated. Aortic stenosis combined with a significant, but not severe reduction in LV function only affects the LV, whereas the RV remains unaffected at this stage of disease. AVR leads to improved LV function and reduced hypertrophy, but without normalization of LV volumes or the LV mass index within 1 year. J. Magn. Reson. Imaging 2000;12:240–246. © 2000 Wiley‐Liss, Inc.