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Biosensor Warning Devices: Reagentless Detection of Modulators of Laccase Activity
Author(s) -
Leech D.,
Feerick K. O.
Publication year - 2000
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/1521-4109(200011)12:16<1339::aid-elan1339>3.0.co;2-c
Subject(s) - biosensor , laccase , chemistry , electrolyte , enzyme , enzyme assay , electrode , biochemistry
We have developed an enzyme activity sensor that functions by detection of the mediated reduction of O 2 in the electrolyte, thus yielding a reagentless system for addressing enzyme activity. Application of the sensor to the detection of modulators of the mediator electrochemistry and of the enzyme has been demonstrated. The potential of the system for monitoring of toxic (to the sensor and to humans) pollution is currently under investigation.