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Voltammetry Study of 2‐Hydroxy‐3‐isopropenyl‐1,4‐naphthoquinone Using a Carbon Paste Electrode
Author(s) -
Ngameni Emmanuel,
Tonle Ignas Kenfack,
Nanseu Charles Peguy,
Wandji Roland
Publication year - 2000
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/1521-4109(200007)12:11<847::aid-elan847>3.0.co;2-9
Subject(s) - carbon paste electrode , electrode , ferrocene , electrochemistry , chemistry , electrolyte , supporting electrolyte , cyclic voltammetry , horizontal scan rate , carbon fibers , inorganic chemistry , nuclear chemistry , combinatorial chemistry , materials science , composite material , composite number
The electrochemical behavior of 2‐hydroxy‐3‐isopropenyl‐1,4‐naphthoquinone also named lapachol, a potent antimalarial agent that also displays activity against various other diseases including some types of cancer, sleeping sickness etc., has been examined. This was achieved by the use of a carbon paste electrode, chemically modified with lapachol. The various parameters that can influence the electrochemical signal (the scan rate of the electrode, the composition of the paste, the pH of the electrolyte) have been scrutinized. The ability of this quinonic compound to serve as a proton donor for the determination of the acidity level of concentrated acids was also investigated: this was achieved by considering the Strehlow's acidity function: Ro(H) which involves the ferricinium/ferrocene couple as a comparison system.