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Dip‐Pen Nanolithography‐Based Methodology for Preparing Arrays of Nanostructures Functionalized with Oligonucleotides
Author(s) -
Zhang H.,
Li Z.,
Mirkin C.A.
Publication year - 2002
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/1521-4095(20021016)14:20<1472::aid-adma1472>3.0.co;2-e
Subject(s) - dip pen nanolithography , nanolithography , materials science , oligonucleotide , nanotechnology , nanostructure , etching (microfabrication) , dna , fabrication , chemistry , medicine , alternative medicine , pathology , biochemistry , layer (electronics)
Arrays of Au nanostructures have been fabricated based on dip‐pen nanolithography and wet chemical etching, whereafter they can be functionalized with alkanethiol‐capped oligonucleotides. These retain their hybridization properties on the surfaces of the nanopatterns and can react with complementary DNA or particles modified with complementary DNA.