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Polyester Microstructures for Topographical Control of Outgrowth and Synapse Formation of Snail Neurons
Author(s) -
Merz M.,
Fromherz P.
Publication year - 2002
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/1521-4095(20020116)14:2<141::aid-adma141>3.0.co;2-r
Subject(s) - materials science , polyester , synapse , microstructure , position (finance) , nanotechnology , silicon , composite material , optoelectronics , neuroscience , biology , finance , economics
Synaptically connected neurons are obtained with defined position of their cell bodies and defined geometry of their arborization using polyester topographical structures (see Figure). The substrates can be used several times. The technique will allow the creation of defined neuronal networks that are stimulated and monitored from silicon chips.