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A Combinatorial and Informatics Approach to CdS Nanoclusters
Author(s) -
Whitling J. M.,
Spreitzer G.,
Wright D. W.
Publication year - 2000
Publication title -
advanced materials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 10.707
H-Index - 527
eISSN - 1521-4095
pISSN - 0935-9648
DOI - 10.1002/1521-4095(200009)12:18<1377::aid-adma1377>3.0.co;2-x
Subject(s) - nanoclusters , informatics , materials science , materials informatics , peptidomimetic , nanotechnology , combinatorial synthesis , health informatics , combinatorial chemistry , dispersity , micelle , rational design , peptide , organic chemistry , chemistry , polymer chemistry , engineering informatics , engineering , biochemistry , medicine , nursing , electrical engineering , public health , aqueous solution
The stabilization of size‐specific monodisperse CdS nanoclusters has received much attention. However, the development of matrices, e.g., polymers, micelles, zeolites, for this purpose has remained largely empirical. Here a combinatorial and informatics approach to the discovery of ligands for CdS nanocluster stabilization is introduced. It is shown that combinatorially derived peptide and peptidomimetic ligands based on phytochelatins can stabilize CdS nanoclusters and that an informatics analysis of the library used yields design parameters critical for obtaining second‐generation ligands.