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Plate Colony Sample Sizes Required for Inferences about the Uniqueness of a Lactobacillus Strain within a Human Volunteer
Author(s) -
Trajstman C.J.
Publication year - 2000
Publication title -
biometrical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 63
eISSN - 1521-4036
pISSN - 0323-3847
DOI - 10.1002/1521-4036(200011)42:7<895::aid-bimj895>3.0.co;2-c
Subject(s) - sample (material) , volunteer , strain (injury) , uniqueness , mathematics , biology , mathematical analysis , physics , ecology , anatomy , thermodynamics
Making inferences about the spectrum of bacterial strains on a plate as a consequence of observing only one strain in a random sample of colonies from the plate is relatively straightforward whereas making inferences about the spectrum of strains within a human volunteer as a consequence of observing only one strain in a random sample from the plate requires some care. The issue of the appropriate number of colonies to sample from a plate to make inferences about strain uniqueness within a human volunteer is examined and illustrated with an example