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RNA‐Aligned Film Prepared from an RNA/Lipid Complex
Author(s) -
Hoshino Yu,
Tajima Sachiko,
Nakayama Hajime,
Okahata Yoshio
Publication year - 2002
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/1521-3927(20020301)23:4<253::aid-marc253>3.0.co;2-h
Subject(s) - rna , cationic polymerization , hydrogen bond , amphiphile , transfer rna , intermolecular force , counterion , chemistry , materials science , crystallography , biochemistry , polymer chemistry , organic chemistry , polymer , molecule , copolymer , ion , gene
Strong films were prepared from an RNA/lipid complex by casting from organic solutions. RNA (mainly tRNA) was extracted from yeasts, followed by a replacement of the sodium counterions of the tRNA phosphate units by cationic amphiphiles. RNA units in the RNA/lipid film could be aligned in one direction by stretching due to the presence of intermolecular hydrogen bonds. The film showed physical strength and was biodegradable.