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Reactivity‐Based One‐Pot Synthesis of a Lewis Y Carbohydrate Hapten: A Colon–Rectal Cancer Antigen Determinant
Author(s) -
Mong KwokKong T.,
Wong ChiHuey
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20021104)41:21<4087::aid-anie4087>3.0.co;2-x
Subject(s) - hapten , colorectal cancer , reactivity (psychology) , chemistry , carbohydrate , antigen , combinatorial chemistry , biochemistry , cancer research , cancer , immunology , medicine , pathology , alternative medicine
The stereospecific synthesis of a tumor‐related carbohydrate antigenic hapten, Lewis Y, from three basic building units 1 – 3 has been achieved by a reactivity‐based one‐pot strategy. RRV=relative reactivity value.