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Transmembrane Signalling
Author(s) -
Barton Patrick,
Hunter Christopher A.,
Potter Timothy J.,
Webb Simon J.,
Williams Nicholas H.
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20021018)41:20<3878::aid-anie3878>3.0.co;2-f
Subject(s) - second messenger system , microbiology and biotechnology , lipid bilayer , signal transduction , membrane transport , chemistry , vesicle , cell surface receptor , intracellular , biophysics , cell membrane , receptor tyrosine kinase , receptor , biology , membrane , biochemistry
Talking through walls : A synthetic system has been developed for transducing a signal across a vesicular bilayer membrane. The external messenger (purple) does not cross the membrane itself, but instigates the release of a secondary messenger (red) on the interior of the vesicle.