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A New Generation of Air Stable, Highly Active Pd Complexes for CC and CN Coupling Reactions with Aryl Chlorides
Author(s) -
Schnyder Anita,
Indolese Adriano F.,
Studer Martin,
Blaser HansUlrich
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20021004)41:19<3668::aid-anie3668>3.0.co;2-u
Subject(s) - aryl , catalysis , in situ , coupling (piping) , chemistry , scheme (mathematics) , combinatorial chemistry , function (biology) , computer science , organic chemistry , materials science , mathematics , metallurgy , alkyl , mathematical analysis , evolutionary biology , biology
High yields in important Pd‐catalyzed reactions of aryl chlorides (see scheme) are obtained with complexes consisting of a palladacycle and a secondary phosphane which could be prepared in situ or isolated. The latter were shown to be stable, and easy to handle in air, and the in situ catalysts allow optimization of the catalyst by variation of the two components.