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An Azulene Dimer as a Near‐Infrared Quencher
Author(s) -
Pham Wellington,
Weissleder Ralph,
Tung ChingHsuan
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20021004)41:19<3659::aid-anie3659>3.0.co;2-q
Subject(s) - azulene , fluorescence , photochemistry , dimer , derivative (finance) , alexa fluor , rhodamine , chemistry , materials science , optics , organic chemistry , physics , financial economics , economics
Turning off the light . A fluorescence quencher based on azulene was synthesized which absorbs light in the range of 650 to 800 nm. Since protease sensing was possible with the derivative shown (Alexa Fluor 680 is the fluorochrome), applications in vivo for imaging molecular targets can be expected.