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Electrocatalytic O 2 Reduction by Synthetic Analogues of the Heme/Cu Site of Cytochrome Oxidase Incorporated in a Lipid Film
Author(s) -
Collman James P.,
Boulatov Roman
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020916)41:18<3487::aid-anie3487>3.0.co;2-y
Subject(s) - cytochrome c oxidase , phospholipid , chemistry , oxidase test , cytochrome c , heme , flux (metallurgy) , diffusion , electron transport chain , biochemistry , combinatorial chemistry , stereochemistry , mitochondrion , enzyme , organic chemistry , physics , membrane , thermodynamics
Close structural analogues (see picture) of the O 2 ‐reducing site of terminal oxidases dispersed in a phospholipid reduce O 2 at physiological potentials and do not release toxic partially reduced oxygen by‐products, even when electron flux is diffusion‐limited.