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An Asymmetric Phase‐Transfer Dihydroxylation Reaction
Author(s) -
Bhunnoo Riaz A.,
Hu Yulai,
Lainé Dramane I.,
Brown Richard C. D.
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020916)41:18<3479::aid-anie3479>3.0.co;2-o
Subject(s) - dihydroxylation , permanganate , enantiomer , transfer (computing) , scheme (mathematics) , phase (matter) , computer science , chemistry , enantioselective synthesis , stereochemistry , information retrieval , organic chemistry , mathematics , catalysis , mathematical analysis , parallel computing
Enantiomerically enriched 1,2‐diols can be prepared, in good enantiomeric excesses, by using a novel asymmetric dihydroxylation of enones with permanganate under phase‐transfer conditions (see scheme: e.g. R 1 = n Bu, R 2 =( p ‐OMe)C 6 H 4 ).