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Highly Diastereo‐ and Enantioselective Intramolecular Amidation of Saturated CH Bonds Catalyzed by Ruthenium Porphyrins
Author(s) -
Liang JiangLin,
Yuan ShiXue,
Huang JieSheng,
Yu WingYiu,
Che ChiMing
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020916)41:18<3465::aid-anie3465>3.0.co;2-d
Subject(s) - ruthenium , intramolecular force , enantioselective synthesis , porphyrin , catalysis , chemistry , medicinal chemistry , stereochemistry , organic chemistry
Virtually complete diastereoselectivity is observed in the intramolecular amidation of saturated CH bonds, catalyzed by the ruthenium porphyrin catalyst 1 or 2 . Reactions of sulfamate esters with PhI(OAc) 2 in the presence of 1 or 2 afforded cyclic sulfamidates in up to 87 % ee.