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Radical Carboazidation of Alkenes: An Efficient Tool for the Preparation of Pyrrolidinone Derivatives
Author(s) -
Renaud Philippe,
Ollivier Cyril,
Panchaud Philippe
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020916)41:18<3460::aid-anie3460>3.0.co;2-6
Subject(s) - pyrrolidinones , chemistry , azide , alkene , intermolecular force , combinatorial chemistry , radical , organic chemistry , component (thermodynamics) , catalysis , molecule , physics , thermodynamics
A one‐pot intermolecular radical carboazidation of alkenes is reported. The utility of the reaction is demonstrated by the development of a three‐component preparation of pyrrolidinones, pyrrolizidinones [Eq. (a)], and indolizidinones starting from benzenesulfonyl azide, terminal alkenes, and 2‐iodoesters.