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Synthesis of Neo‐Peptidoglycans: An Unexpected Activity of Proteases
Author(s) -
Wehofsky Nicole,
Löser Reik,
Buchynskyy Andrij,
Welzel Peter,
Bordusa Frank
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020802)41:15<2735::aid-anie2735>3.0.co;2-e
Subject(s) - moiety , chemistry , peptide , carboxylate , carbohydrate , combinatorial chemistry , proteases , coupling (piping) , biochemistry , computer science , stereochemistry , enzyme , materials science , metallurgy
Carbohydrate coupling at any desired peptide carboxylate moiety is possible with a highly selective biocatalytic route for the synthesis of carbohydrate–peptide conjugates (see picture).