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Aminocyclopentadienyl Ruthenium Chloride: Catalytic Racemization and Dynamic Kinetic Resolution of Alcohols at Ambient Temperature
Author(s) -
Choi Jun Ho,
Kim Yu Hwan,
Nam Se Hyun,
Shin Seung Tae,
Kim MahnJoo,
Park Jaiwook
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020703)41:13<2373::aid-anie2373>3.0.co;2-7
Subject(s) - racemization , ruthenium , kinetic resolution , chloride , catalysis , kinetic energy , chemistry , resolution (logic) , organic chemistry , computer science , enantioselective synthesis , physics , quantum mechanics , artificial intelligence
Ruthenium–enzyme tandem catalysis : The novel racemization catalyst 1 improves the dynamic kinetic resolution (DKR) of secondary alcohols dramatically. The DKR proceeds at room temperature with isopropenyl acetate as an acyl donor. In addition, the DKR is faster even with much less lipase than in previous DKRs.