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Calixarene‐Type Macrocycles by Oxidation of Phenols Related to Vitamin E
Author(s) -
Rosenau Thomas,
Potthast Antje,
Hofinger Andreas,
Kosma Paul
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020402)41:7<1171::aid-anie1171>3.0.co;2-c
Subject(s) - calixarene , chemistry , derivative (finance) , redox , type (biology) , sequence (biology) , vitamin e , combinatorial chemistry , oxidation reduction , organic chemistry , computer science , stereochemistry , molecule , biochemistry , business , biology , antioxidant , ecology , finance
It might not be as healthy as vitamin E , but the α ‐tocopherol derivative 1 undergoes all the typical reactions of the vitamin twice, as a result of its “siamese twin” character. The transformation of 1 in a three‐step reaction sequence of oxidation, hetero‐Diels–Alder reaction, and reduction provides facile access to tetrameric calixarene‐type macrocycles 2 .