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Preparation of New Functionalized Cyclopropylmagnesium Reagents
Author(s) -
Vu Viet Anh,
Marek Ilan,
Polborn Kurt,
Knochel Paul
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020118)41:2<351::aid-anie351>3.0.co;2-5
Subject(s) - electrophile , reagent , magnesium , german , yield (engineering) , foundation (evidence) , chemistry , combinatorial chemistry , organic chemistry , materials science , philosophy , political science , law , catalysis , metallurgy , linguistics
An I–Mg or Br–Mg exchange reaction has enabled ester‐functionalized cyclopropylmagnesium derivatives including magnesium carbenoids to be prepared for the first time in high yield. These magnesium reagents are configurationally stable and react stereoselectively with electrophiles (see scheme).