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Total Synthesis of Ambruticin
Author(s) -
Lee Eun,
Choi Seung Jib,
Kim Hahn,
Han Hee Oon,
Kim Young Keun,
Min Sun Joon,
Son Sung Hee,
Lim Sang Min,
Jang Won Suk
Publication year - 2002
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20020104)41:1<176::aid-anie176>3.0.co;2-#
Subject(s) - chemistry
Highly stereoselective radical cyclization and olefin metathesis reactions for the construction of oxacyclic building blocks were key steps in the convergent total synthesis of the orally active antifungal agent ambruticin ( 1 ).