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Ru‐ and Rh‐Catalyzed Asymmetric Hydrogenations: Recent Surprises from an Old Reaction
Author(s) -
Rossen Kai
Publication year - 2001
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/1521-3773(20011217)40:24<4611::aid-anie4611>3.0.co;2-4
Subject(s) - catalysis , enantioselective synthesis , catalytic cycle , chemistry , substrate (aquarium) , rhodium , hydrogen , ionic bonding , ruthenium , ionic liquid , organic chemistry , ion , oceanography , geology
Far from being a well‐understood reaction , the enantioselective hydrogenation of prochiral olefins with Rh–and Ru–bisphosphane catalysts (see picture, M=Rh, Ru) has recently shown some surprises. Among them are a catalytic cycle featuring initial addition of hydrogen to the catalyst and not the catalyst–substrate complex as well as a purely ionic mechanism.